Steroids and derivatives
Cayman Chemical EstradIol 3 DGlucuronIde 25mg
A non-cholestatic regioisomer of E217G that acts as a substrate for MRP2, competing with E217G for MRP2-mediated transport (IC50 = 14.2 µM)
Cayman Chemical 2-bromo 17-EstradIol 50mg
A synthetic steroid and inhibitor of estrogen 2-hydroxylase; inhibits estrogen 2-hydroxylase in rat liver microsomes at 50 and 100 µM; prevents estrogen-induced inhibition of apomorphine-induced climbing behavior in mice at 5 mg/kg
Medchemexpress LLC β-Estradiol 17-acetate | 1743-60-8 | 99.9% | 1 ML
β-Estradiol 17-acetate is a metabolite of estradiol, designed for research use only in laboratory settings. It is provided for chemical synthesis and intended for use by experienced personnel in appropriately equipped facilities.
- Available in powder and pre-dissolved solution formats.
- Stable under recommended storage conditions, with specific guidance for powder and solvent forms.
- Highly soluble in DMSO for in vitro applications.
- Features established protocols for in vivo solubility using various solvent systems.
- Molecular formula C20H26O3 and molecular weight of 314.42.
- Typically appears as a white to off-white solid with a melting point of 119°C.
Medchemexpress LLC Alpha-Estradiol (Standard) | 57-91-0 | 99.93% | 25 MG
Alpha-Estradiol (Standard) is the analytical standard of Alpha-Estradiol, intended for research and analytical applications. It is a weak estrogen and a 5α-reductase inhibitor used as a topical medication in the treatment of androgenic alopecia.
- Reference standard supplied assay
- Commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS
Sigma Aldrich Fine Chemicals Biosciences -Estradiol-Water Soluble BioReagent, suitable for cell culture, MFCD00133134
-Estradiol-Water Soluble BioReagent, suitable for cell culture
Medchemexpress LLC Estradiol (hemihydrate) | 35380-71-3 | 99.32% | 100 MG
Estradiol (hemihydrate) | 35380-71-3 | 99.32% | 100 MG
Sigma Aldrich Fine Chemicals Biosciences Ethinyl estradiol Related Compound B United States Pharmacopeia (USP) Reference Standard | 1231-96-5 | 20MG
Ethinyl estradiol Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 294.39 | 1231-96-5 | 20MG
Sigma Aldrich Fine Chemicals Biosciences beta Estradiol 17 beta D g25MG
beta Estradiol 17 beta D g25MG
Medchemexpress LLC Estra-1,3,5(10)-triene-3,17-diol (17β)-, 17-(hydrogen butanedioate) | 7698-93-3 | 98.8% | 372.45 | 100 MG
β-Estradiol 17-hemisuccinate is a synthetic derivative of estradiol. This compound is a white to off-white solid with a purity of 98.8%. It is suitable for research applications.
- Synthetic derivative of estradiol
- Purity of 98.8%
- Molecular weight of 372.45
- White to off-white solid appearance
- Store at 4°C under nitrogen
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- Soluble in DMSO
Medchemexpress LLC Estra-1,3,5(10)-triene-3,17-diol (17β)-, 17-(hydrogen butanedioate) | 7698-93-3 | 98.8% | 372.45 | 50 MG
β-Estradiol 17-hemisuccinate is a synthetic derivative of estradiol, appearing as a white to off-white solid.
- Synthetic derivative of estradiol.
- CAS number: 7698-93-3.
- Molecular weight: 372.45.
- Chemical formula: C22H28O5.
- Purity: 98.8%.
- Store at 4°C, stored under nitrogen.
- Store in solvent at -80°C for 6 months or -20°C for 1 month, stored under nitrogen.
- 1H NMR spectrum and LCMS consistent with structure.
Medchemexpress LLC Estra-1,3,5(10)-triene-2,4,16,16-d4-3,17-diol, 3-(hydrogen sulfate), sodium salt, (17a)- | 352431-50-6 | 99.6% | 378.45 g/mol | C18H19D4NaO5S | 5 MG
17β-Estradiol sulfate-d4 (sodium) is a deuterium-labeled sodium salt of 17β-estradiol 3-sulfate supplied as a high-purity analytical standard for research use. It is intended as an internal standard or tracer in mass spectrometry and other quantitative assays to study estradiol metabolism and sulfate conjugates.
- Deuterium-labeled (d4) analog for isotope dilution and tracer studies.
- Sodium salt supplied as a solid, suitable for long-term storage.
- High purity (~99.6%) for analytical applications.
- Molecular formula C18H19D4NaO5S; molecular weight 378.45 g/mol.
- For research use only; not for human or clinical use.
Cayman Chemical Ethynyl Estradiol
An estrogen receptor agonist (EC50 = 8.5 pM in a reporter assay using T47D cells); reduces serum cholesterol levels and femur bone mass and increases uterine mass in an OVX rat model of postmenopause at 0.1 mg/kg per day; has been found in wastewater effluent; prevents secondary sexual development in male fathead minnows and increases the numbers of intersex fish at 4 ng/l
Medchemexpress LLC Estradiol cypionate | 313-06-4 | MFCD00056558 | 99.5% | 1 ML
Estradiol cypionate is the 17β-cypionate ester of Estradiol, inhibiting ET-1 synthesis by acting on estrogen receptors. It is intended for research use only. In vitro, it inhibits proliferation of gastric cancer cells and induces G1/S phase cell cycle arrest and apoptosis by affecting the PI3K/Akt/mTOR pathway. In vivo, it increases cortical bone density in ovariectomized rabbits, increases occurrence of estrus and pregnancy in cows, and inhibits tumor growth in MGC803 nude mice tumor models.
- Inhibits gastric cancer cell proliferation
- Induces G1/S phase cell cycle arrest and apoptosis
- Increases cortical bone density
- Promotes estrus and pregnancy
- Inhibits tumor growth
Apexbio Technology LLC α-Estradiol 57-91-0 10mM (in 1mL Ethanol)
alpha-Estradiol (57-91-0) is a small-molecule inhibitor targeting 5 -reductase the enzyme responsible for converting testosterone to dihydrotestosterone (DHT) It is designed to inhibit 5 -reductase activity thereby modulating androgen metabolism and androgen-related signaling pathways alpha-Estradiol exerts its biological activity primarily through enzyme inhibition In reported experimental studies alpha-Estradiol demonstrates inhibitory activity against 5 -reductase with an IC50 value ranging from approximately 1 to 10 M though the precise value may depend on assay conditions Based on these pharmacological properties alpha-Estradiol holds research potential in the treatment and study of androgenetic alopecia